Hairy cell leukemia flow
Hairy cell leukemia - Symptoms and causes - Mayo Clinic
In hairy cell leukemia, the" hairy cells" (malignant B lymphocytes) accumulate in the bone marrow, It is also possible to definitively diagnose hairy cell leukemia through flow cytometry on blood or bone marrow. The hairy cells are larger than normal and positive for CD19, CD20, CD22,
Distinguishing hairy cell leukemia variant from hairy cell
Used to diagnose hairy cell leukemia and hairy cell leukemiavariant. Specimen Requirements Flow cytometry testing can be performed on bone marrow aspirate, peripheral blood, fresh bone marrow core biopsy, unfixed tissue, and body fluids.
Hairy Cell Leukemia HCL Add-On Flow Panel
Hairy cells are larger than normal and positive for CD19, CD20, CD22, CD11c, CD25, CD103, and FMC7. Hairy cell leukemiavariant (HCLV), which shares some characteristics with B cell prolymphocytic leukemia (BPLL), does not show CD25 (also called the Interleukin2 receptor, alpha).